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Dreno B., Rougier A., Seite S. International observational study on the management of acneic patients.
To evaluate the management of acneic patients in private practice, dermatologists from 16 countries all over the world were asked about their management of 6,345 young patients with mild to moderate acne. Read the poster
Seite S., Rougier A., Dreno B. Enquête sur la prise en charge des patients acnéiques en France. An investigational study of acne treatment in France
To evaluate current treatment approaches, more than 252 French dermatologists were asked about their preferred treatments, other than isotretinoin, for young acneic patients… Read the abstract (in french)
Seite S., Caixeta C., Towersey L. Large-scale survey to describe acne management in Brazilian clinical practice.
To assess the therapeutic choices made by Brazilian dermatologists for grade I, II, III, and IV acne, 596 dermatologists in private practice in 12 states of Brazil were interviewed. Download the publication
Acne and pollution
Seite S., Moyal D. Effects of air pollution on sebum rate and acne: how to manage acneic skin in a polluted environment
To evaluate the effect of pollution on sebum rate and acne, and the efficiency of a skin care product routine (purifying foaming gel + skin care dedicated to acneic patient + high UVA/UVB protection level sun care), 64 Chinese women and men were recruited. Read the poster
Krutmann J., Moyal D., Liu W., et al. Pollution and acne: is there a link?
To review the current evidence that links air pollution to worsening of acne symptoms, a group of five Asian and three European scientists with expertise in dermatology reviewed the current literature. Download the publication
Liu W., Pan X., Vierkötter A., et al. A time-series study of the effect of air pollution on outpatient visits for acne vulgaris in Beijing
To assess the association between ambient air pollutant concentrations and the number of visits of patients for acne vulgaris to a dermatological outpatient clinic, 59,325 outpatient visits were recorded and daily air pollution parameters for PM 10, PM 2.5, SO 2, and NO 2 were obtained from the Beijing Municipal Environmental Monitoring Center. Read the abstract
Acne and microbiota
Dreno B, Martin R, Moyal D, Henley JB, Khammari A, Seité S. Skin microbiome and acne vulgaris: staphylococcus, a new actor in acne.
This exploratory study investigated the characteristics of the skin microbiota in 55 subjects with mild to moderate acne (with at least 20 comedones and 10 papulo-pustular lesions equally distributed over the face) and determined microbiota changes after 28 days of application of erythromycin 4% or a dermocosmetic, … Read the poster Read the publication
Bieber T., Dreno B., Seite S. The Skin Microbiome in Patients with Acne Vulgaris
Understand the interactions between skin microbiota and the innate immune response in acne may provide a platform to design efficacious treatment strategies, specifically concerning the role of dermo-cosmetics to protect the skin microbiota. This issue was the subject of a symposium, which took place in October 2015, as part of the European Academy of Dermatology and Venereology Congress (Copenhagen, Denmark), … Read the publication
Dagnelie M-A., Montassier E., Khammari A., Mounier C., Corvec S., Dréno B. Inflammatory skin is associated with changes in the skin microbiota composition on the back of severe acne patients. specifically concerning the role of dermo-cosmetics to protect the skin microbiota.
Skin microbiota appears as a key player involved in several skin dermatoses physiopathology. Here, we show that inflammatory skin is associated with changes in the skin microbiota composition on the back of severe acne patients but also on the face of patients where acne was scored as mild to moderate, comparing with healthy controls. Read the publication
Clinical studies with emollients
Saint-Jean M., Khammari A., Seite S., et al. Characteristics and control of the premenstrual acne flare up with a dermocosmetic: double blind randomized trial.
This comparative randomzsed study performed on 32 women with premenstrual acne syndrome reveals the benefit of a facial care regimen combined with a dermo-cosmetic Read the poster Read the abstract
Wang X., Zhaoxia L., Dan Z., et al. A double blind, randomized, placebo controlled clinical bilateral trial evaluating the efficacy and safety of a new formulation in acneic patients with risks of post-inflammatory hyper-pigmented lesions.
To demonstrate the interest of a dermo-cosmetic formula containing anti-inflammatory ingredients in the prevention of the appearance of post-inflammatory hyper-pigmented lesions, a double blind, randomized, placebo controlled, bilateral (split-face) comparison was conducted on 35 Chinese subjects with mild to moderate acne Read the poster
Seite S., Moyal D. Observational study on patients with acne and at risk of PIH.
To evaluate the use of a topical formula containing ingredients (niacinamide, procerad, LHA, piroctone, olamine, linoleic acid) to reduce acne lesions and post-inflammatory hyperpigmentation, alone or in adjunctive therapy, 5,232 patients with mild to moderate acne were followed during 2 months Read the poster
Kim M-R., Kerrouche N. Combination of benzoyl peroxide 5% gel with liquid cleanser and moisturizer SPF 30 in acne treatment results in high levels of subject satisfaction, good adherence and favorable tolerability
To evaluate patients’ satisfaction after use of BPO 5% gel in combination with liquid cleanser and moisturizer SPF 30, an open-label study was conducted in fifty subjects with mild-to-moderate facial acne Download the publication
Adjunctive therapy
Del Rosso J.Q. The Role of Skin Care as an Integral Component in the Management of Acne Vulgaris Part 1: The Importance of Cleanser and Moisturizer Ingredients, Design, and Product Selection. J Clin Aesthet Dermatol. 2013;6(12):19–27. Link to free full text
Goh C.L., Noppakun N., Moccali G., et al. Meeting the Challenges of Acne Treatment in Asian Patients: A Review of the Role of Dermocosmetics as Adjunctive Therapy. J Cutan Aesthet Surg. 2016; 9(2): 85–92. Link to free full text
Lynde C. W., Andriessen A., Barankin B., et al. Moisturizers and Ceramide-containing Moisturizers May Offer Concomitant Therapy with Benefits. J Clin Aesthet Dermatol. 2014;7(3) Link to free full text
Munehiro A., Murakami Y., Shirahige Y., et al. Combination effects of cosmetic moisturisers in the topical treatment of acne vulgaris. J Dermatolog Treat. 2011;23(3):172-6. Link to abstract
Feldman S.R., Chen D.M. How patients experience and manage dryness and irritation from acne treatment. J Drugs Dermatol. 2011;10(6):605–8. Link to abstract
Draelos Z.D. Therapeutic moisturizers. Dermatol Clin. 2000;18(4):597–607. Link to abstract
Lynde C.W. Moisturizers: what they are and how they work. Skin Therapy Lett. 2001;6(13):3–5. Link to abstract
Matsuoka Y., Yoneda K., Sadahira C., et al. Effects of skin care and makeup under instructions from dermatologists on the quality of life of female patients with acne vulgaris. J Dermatol. 2006 Nov;33(11):745-52. Link to abstract
Rougier A.M., Richard A. Efficacy and safety of new salicylic acid derivative as a complement of vitamin A acid in acne treatment Eur J Dermatol. 2002 Jul-Aug;12(4):XLIX-L. Link to abstract
Rougier A.M., Dréno B., Khammari A., et al. Interest of new salicylic acid derivative in the prevention of acne relapses. Eur J Dermatol. 2002 Jul-Aug;12(4):LI-LIII. Link to abstract
Solomon B.A., Shalita A.R. Effects of detergents on acne. Clin Dermatol. 1996 Jan-Feb;14(1):95-9. Link to free full text
Diet and acne
Pappas A. The relationship of diet and acne A review. Dermato-Endocrinology 2009 ; 1:5, 262-7 Link to the free full text
Quynh-Giao Nguyen Q-G., Markus R., Katta R. Diet and acne: an exploratory survey study of patient beliefs. Dermatol Pract Concept 2015;6(2):21-7. Link to the free full text
Zaenglein A.L., Pathy A.L., Bethanee J. Schlosser B.J., et al. Guidelines of care for the management of acne vulgaris. J Am Acad Dermatol 2016;74:945-73. Link to the free full text
Smith R.N., Mann N.J., Braue A., et al. A low-glycemic-load diet improves symptoms in acne vulgaris patients: a randomized controlled trial. Am J Clin Nutr 2007;86:107–15. Link to the free full text
American Academy of Dermatology. Growing evidence suggests possible link between diet and acne Link to free full text
Romańska-Gocka K., Woźniak M., Kaczmarek-Skamira E., Zegarska B. The possible role of diet in the pathogenesis of adult female acne Adv Dermatol Allergol 2016; XXXIII (6): 416–20. Link to the free full text
Spencer E.H., Ferdowsian H.R., Barnard N.D. Diet and acne: a review of the evidence. International Journal of Dermatology 2009, 48, 339–347 Link to the free full text
Nast A., Dreno B., Bettoli V., et al. European evidence-based (S3) guidelines for the treatment of acne. J Eur Acad Dermatol Venereol. 2012 ;26(supp 1) :1-29. Shokeen D. Influence of Diet in Acne Vulgaris and Atopic Dermatitis. Cutis. 2016;98:E28-E29. Link to the free full text
Eichenfield L. F., Krakowski A. C., Caroline Piggott C., et al. Evidence-Based Recommendations for the Diagnosis and Treatment of Pediatric Acne. Pediatrics 2013;131:S163–S186. Link to the free full text