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Richters RJ, Uzunbajakava NE, Falcone D, Hendriks JC, Jaspers EJ, van de Kerkhof PC, van Erp PE. Clinical, biophysical and immunohistochemical analysis of skin reactions to acute skin barrier disruption — a comparative trial between participants with sensitive skin and those with nonsensitive skin.
The study aimed to identify key features in the morphology and physiology of skin reactions and recovery in participants with sensitive skin… Read the study
Pinto P, Rosado C, Parreirão C, Rodrigues LM. Is there any barrier impairment in sensitive skin?: a quantitative analysis of sensitive skin by mathematical modeling of transepidermal water loss desorption curves.
Aimed to investigate the cutaneous barrier integrity of individuals with sensitive skin using a novel approach: a plastic occlusion stress test followed by measurement of transepidermal water loss (TEWL) desorption curves… Read the study
Kvenshagen BK, Carlsen KH, Mowinckel P, Berents TL, Carlsen KC. Can early skin care normalise dry skin and possibly prevent atopic eczema? A pilot study in young infants.
The study aimed to assess if xerosis, and possibly AE, could be reduced at six months of age by early introduction of frequent oil baths/facial fat cream in infants with dry skin… Read the study
Richters RJ, Falcone D, Uzunbajakava NE, Varghese B, Caspers PJ, Puppels GJ, van Erp PE, van de Kerkhof PC. Sensitive Skin: Assessment of the Skin Barrier Using Confocal Raman Microspectroscopy.
The aim of this study was to investigate the skin barrier molecular composition in sensitive skin (SS) subjects using confocal Raman microspectroscopy, and to compare it with that of non-SS (NSS) individuals as well as atopic dermatitis and allergic rhinoconjunctivitis subjects, who frequently report SS… Read the study
Bornkessel A, Flach M, Arens-Corell M, Elsner P, Fluhr JW. Functional assessment of a washing emulsion for sensitive skin: mild impairment of stratum corneum hydration, pH, barrier function, lipid content, integrity and cohesion in a controlled washing test.
The purpose of the study was to assess the effect of an improved washing solution for sensitive skin in a half-site comparison on barrier-related parameters… Read the study
Gueniche A, Philippe D, Bastien P, Reuteler G, Blum S, Castiel-Higounenc I, Breton L, Benyacoub J. Randomised double-blind placebo-controlled study of the effect of Lactobacillus paracasei NCC 2461 on skin reactivity.
A randomized double-blind placebo-controlled clinical study with two-month supplementation of Lactobacillus paracasei in two female treatment groups (n=32 per group)… Read the study
Sensitive skin causes
Seite S, Misery L. Skin sensitivity and skin microbiota: Is there a link? 2018 Sep;27(9):1061-1064. doi: 10.1111/exd.13686. Epub 2018 Jul 30. Read the abstract
Video – Skin sensitivity and skin microbiota: Is there a link?
Misery L. Sensitive skin. J Eur Acad Dermatol Venereol. 2016 Feb;30 Suppl 1:2–8. Link to abstract
Berardesca E et al. Sensitive skin: an overview. Int J Cosmet Sci. 2013 Feb;35(1):2–8. Link to abstract
Zeeuwen PL et al. Microbiome and skin diseases. Curr Opin Allergy Clin Immunol. 2013 Oct;13(5):514–20. Link to abstract
Baldwin HE et al. The Role of Cutaneous Microbiota Harmony in Maintaining a Functional Skin Barrier. J Drugs Dermatol. 2017 Jan 1;16(1):12–18. Link to abstract
Barnes L et al. Topical corticosteroid-induced skin atrophy: a comprehensive review. Drug Saf. 2015 May;38(5):493–509. Link to abstract
Farage MA et al. Sensitive skin: closing in on a physiological cause. Contact Dermatitis. 2010 Mar;62(3):137–49. Link to abstract
Seidenari S et al. Baseline biophysical parameters in subjects with sensitive skin. Contact Dermatitis. 1998 Jun;38(6):311–5. Link to abstract
Mills OH Jr, Berger RS. Defining the susceptibility of acne-prone and sensitive skin populations to extrinsic factors. Dermatol Clin 1991;9:93–98. Link to abstract
Paquet F, Piérard-Franchimont C, Fumal I, Goffin V, Paye M, Piérard GE. Sensitive skin at menopause; dew point and electrometric properties of the stratum corneum. Maturitas 1998;28:221–227. Link to abstract
Seidenari S, Francomano M, Mantovani L. Baseline biophysical parameters in subjects with sensitive skin. Contact Dermatitis 1998;38:311–315.
Misery L, Myon E, Martin N, Consoli S, Boussetta S, Nocera T, et al. Sensitive skin: psychological effects and seasonal changes. J Eur Acad Dermatol Venereol 2007;21:620–628. Link to abstract
Saint-Martory C, Roguedas-Contios AM, Sibaud V, Degouy A, Schmitt AM, Misery L. Sensitive skin is not limited to the face. Br J Dermatol 2008;158:130–133. Link to abstract
Farage MA, Katsarou A, Maibach HI. Sensory, clinical and physiological factors in sensitive skin: a review. Contact Dermatitis 2006;55:1–14. Link to abstract
Kligman AM, Sadiq I, Zhen Y, Crosby M. Experimental studies on the nature of sensitive skin. Skin Res Technol 2006;12:217–222. Link to abstract
Marriott M, Holmes J, Peters L, Cooper K, Rowson M, Basketter DA. The complex problem of sensitive skin. Contact Dermatitis 2005;53:93–99. Link to abstract
Lev-Tov H, Maibach HI. The sensitive skin syndrome. Indian J Dermatol 2012;57:419–423. Link to the free full text
Querleux B, Dauchot K, Jourdain R, Bastien P, Bittoun J, Anton JL, et al. Neural basis of sensitive skin: an fMRI study. Skin Res Technol 2008;14:454–461. Link to abstract
Stander S, Schneider SW, Weishaupt C, Luger TA, Misery L. Putative neuronal mechanisms of sensitive skin. Exp Dermatol 2009;18:417–423. Link to abstract
Sensitive skin diagnoses
Farage MA. Self-reported immunological and familial links in individuals who perceive they have sensitive skin. Br J Dermatol. 2008 Jul;159(1):237–8. Link to abstract
Farage MA. How do perceptions of sensitive skin differ at different anatomical sites? An epidemiological study. Clin Exp Dermatol 2009;34:e521–e530. Link to abstract
Guinot C, Malvy D, Mauger E, Ezzedine K, Latreille J, Ambroisine L, et al. Self-reported skin sensitivity in a general adult population in France: data of the SU.VI.MAX cohort. J Eur Acad Dermatol Venereol 2006;20:380–390. Link to abstract
Primavera G, Berardesca E. Sensitive skin: mechanisms and diagnosis. Int J Cosmet Sci 2005;27:1–10. Link to abstract
Diogo L, Papoila AL. Is it possible to characterize objectively sensitive skin? Skin Res Technol 2010;16:30–37. Link to abstract
Green BG. Measurement of sensory irritation of the skin. Am J Contact Dermat 2000;11:170–180. Link to abstract
Roussaki-Schulze AV, Zafiriou E, Nikoulis D, Klimi E, Rallis E, Zintzaras E. Objective biophysical findings in patients with sensitive skin. Drugs Exp Clin Res 2005;31(suppl):17–24. Link to abstract
Robinson MK, Perkins MA. Evaluation of a quantitative clinical method for assessment of sensory skin irritation. Contact Dermatitis 2001;45:205–213. Link to abstract
Kim SJ, Lim SU, Won YH, An SS, Lee EY, Moon SJ, et al: The perception threshold measurement can be a useful tool for evaluation of sensitive skin. Int J Cosmet Sci 2008;30:333–337. Link to abstract
Misery L, et al. Sensitive skin in children. Acta Derm Venereol 2020;100(1):1-2. Link to the free full text
Allergies
Baviera G et al. Microbiota in healthy skin and in atopic eczema. Biomed Res Int. 2014;2014:436921. Link to the free full text
Boguniewicz M et al. Atopic dermatitis: a disease of altered skin barrier and immune dysregulation. Immunol Rev. 2011 Jul;242(1):233–46. Link to the free full text
Seite S et al. Microbiome of affected and unaffected skin of patients with atopic dermatitis before and after emollient treatment. J Drugs Dermatol. 2014 Nov;13(11):1365–72. Link to abstract
Thestrup-Pedersen K Clinical aspects of atopic dermatitis. Clin Exp Dermatol. 2000 Oct;25(7):535–43. Link to abstract
Hanifin JM. Guidelines of care for atopic dermatitis, developed in accordance with the American Academy of Dermatology (AAD)/American Academy of Dermatology Association "Administrative Regulations for Evidence-Based Clinical Practice Guidelines". J Am Acad Dermatol. 2004 Mar;50(3):391–404. Link to abstract
Oszukowska M. Role of primary and secondary prevention in atopic dermatitis. Postepy Dermatol Alergol. 2015 Dec;32(6):409–20. Link to the free full text
Horimukai K.J. Application of moisturizer to neonates prevents development of atopic dermatitis. Allergy Clin Immunol. 2014 Oct;134(4):824–830.e6. Link to abstract
Marenholz I et al. The genetics of the skin barrier in eczema and other allergic disorders. Curr Opin Allergy Clin Immunol. 2015 Oct;15(5):426–34. Link to abstract
Egawa G et al. Multifactorial skin barrier deficiency and atopic dermatitis: Essential topics to prevent the atopic march. J Allergy Clin Immunol. 2016 Aug;138(2):350–358.e1. Link to abstract
Drucker AM. Atopic dermatitis: Burden of illness, quality of life, and associated complications. Allergy Asthma Proc. 2017 Jan 1;38(1):3–8. Link to abstract
Kunz B et al. Clinical validation and guidelines for the SCORAD index: consensus report of the European Task Force on Atopic Dermatitis. Dermatology. 1997;195(1):10–9. Link to abstract
Schmitt J et al. Assessment of clinical signs of atopic dermatitis: a systematic review and recommendation. J Allergy Clin Immunol. 2013 Dec;132(6):1337–47. Link to abstract
Misery L et al. Nine-year follow-up of children with atopic dermatitis by general practitioners. Dermatology. 2014;228(4):344–9. Link to abstract
Treatments
Berardesca E, Maibach HI. Sensitive and ethnic skin. A need for special skin-care agents? Dermatol Clin 1991;9:89–92. Link to abstract
Muizzuddin N, Marenus KD, Maes DH. Factors defining sensitive skin and its treatment. Am J Contact Dermat 1998;9:170–175. Link to abstract
Draelos ZD. Sensitive skin: Perceptions, evaluation, and treatment. Am J Contact Dermat 1997;8:67–78. Link to abstract
Draelos ZD. Sensitive skin: Perceptions, evaluation, and treatment. Am J Contact Dermat 1997;8:67–78. Link to abstract
Kueper T, Krohn M, Haustedt LO, Hatt H, Schmaus G, Vielhaber G. Inhibition of TRPV1 for the treatment of sensitive skin. Exp Dermatol 2010;19:980–986. Link to abstract
Heinicke IR, Adams DH, Barnes TM, Greive KA. Evaluation of a topical treatment for the relief of sensitive skin. Clin Cosmet Investig Dermatol 2015;8:405–412. Link to the free full text
Isoda K, Seki T, Inoue Y et al. Efficacy of the combined use of a facial cleanser and moisturizers for the care of mild acne patients with sensitive skin. J Dermatol 2015;42:181–188. Link to abstract
Xie Z, Lan Y. Effectiveness of pimecrolimus cream for women patients with sensitive skin and its underlying mechanism. Zhongguo yi xue ke xue Yuan xue bao 2012;34:375–378. Link to abstract
Choi M, Kim JE, Cho KH, Lee JH. In vivo and in vitro analysis of low level light therapy: a useful therapeutic approach for sensitive skin. Lasers Med Sci 2013;28:1573–1579. Link to abstract