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Sphingobioma: a new and unique ingredient to restore microbiome functions
- May. 2022
- Supported by
Sphingobioma is a unique bacterial strain extracted from La Roche-Posay thermal water among 400 bacterial strains. It is a non-pathogenic, flagellated and gram negative bacteria that does not possess Lipopol-ysaccharids (LPS). Its cell membrane contains glycosphingolipids (GSLs).
Its manufacturing process is marked with the "green sciences" stamp.
In vitro research showed SPHINGOBIOMA™ induces IL-10 production in human lymphocytes. IL-10 are anti-inflammatory mediators and they train skin not to over-react to allergens. This unique bacterium therefore restores the microbiome functions.
After treatment with SPHINGOBIOMA™. Green florescent staining indicating intracellular IL-10. Colour intensity is correlated with IL-10 concentration.
SPHINGOBIOMA™ has 3 properties:
1) MICROBIOME
It is respectful of the five skin commensal strains:- S. epidermidis,
- S. aureus,
- C. acnes,
- M. furfur,
- C. xerosis.
2) EPIDERMAL BARRIER
It improves tight junctions, it reinforces barrier function, it stimulates SASPase activity and it reduces desquamation.3) IMMUNOMODULATION
It inhibits pro-inflammatory mediators and IgE production and it induces IL-10 production to train skin not to overt-react to allergens.