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Pioneering microbiome science for the last 10 years

Life changing skincare prescribed by dermatologists

Lipikar AP+MAX

Itch control | Instant dry skin relief | Anti-relapse

Triple-action emollient-plus balm for ultra-dry to atopic-prone skin.

Proprietary Neurobioma technology to tackle itch, restore the skin barrier, and rebalance the skin microbiome.

PROVEN RESULTS

Tested on atopic skin and in oncology patients under dermatological, ophthalmological and pediatric control

Visible efficacy

ELIGIBLE PATIENTS

Suitable from 0 to 100 years old, even for newborns – all skin tones (Fitzpatrick I-VI)

From newborns

Suitable from birth

FAQ

How does it compare to 10% urea? ▼

Superior on all measures at Week 12 in a double-blind RCT (N=60): better SCORAD, TEWL, DLQI, hydration, and skin pH (Prakoeswa, 2025). Confirmed in a second independent RCT (Canchy et al., ISAD, 2024).

Is it safe for newborns? ▼

Yes. Tested under dermatological and paediatric control from the first days of life, with high response rates and good tolerance (Canchy et al., WCPD, 2025).

When do results appear? ▼

TEWL improvement vs urea is measurable from Week 4. Significant differences in SCORAD, DLQI, and hydration emerge between Week 8 and Week 12 (Prakoeswa, 2025).

Does it reduce steroid use? ▼

Yes — 31% less corticosteroid by weight vs standard emollient in a 28-day RCT (N=119; p=0.041) (Zelenkova, 2023).

What about patients with darker skin tones? ▼

Studies across Fitzpatrick I–VI confirm increased NMF levels and improved itch intensity across all skin tones (La Roche-Posay, AAD, 2025).

Clinical Evidence

Before (D0)

After (D28)

Proven results

Tested on skins with atopic background

6H

Visible efficacy

Effect after 6h, dry skin relief for long-lasting hydration

24H

Itch control

For a better quality of life day & night

72H

Moisturizing effect on all skin tones

Long lasting relief for ultra dry to atopic prone skin

*Clinical study, 75 subjects, 72h after stopping the product use once daily for 28 days.
**Consumer study on 139 subjects presenting itch sensations due to dryness. Result 24h after stopping product use following 15 days of product application once a day.

Proven results

Significant anti-inflammatory effects observed

*Studies conducted on a reconstructed human epidermis model mimicking atopic dermatitis

* TSLP (thymic stromal lymphopoietin), RANTES (regulated on activation,
normal T-cell expressed and secreted), and CCL2 (C-C Motif Chemokine
Ligand 2)

Safety

Tested under dermatological and ophthalmological control on adults
Tested under dermatological and pediatrics control on children and babies
Tested on skins with atopic background
Suitable for patients undergoing cancer treatments
Suitable from 1st days of life

Ingredient Science

Explore the science behind the formula and how key ingredients work together to target the biological mechanisms underlying the skin concern

KEY ACTIVE COMPLEX

Neurobioma: Proteasyl + Aqua Posae Filiformis + Microresyl

NEUROBIOMA TECHNOLOGY

Cutting edge technology inspired from advanced neurosciences research connecting microbiome and neuro-sensorial perception of itch. It helps to reduce itch sensations.

FULL LABELLING

Neurobioma Mode of Action

Novel Itch Pathway Linking S.Aureus Exotoxin to Itch in AD Patients

Access the full publication

Access the publication

Routine

Morning

STEP 1 CLEANSE

LIPIKAR SYNDET AP+

STEP 1 CLEANSE

LIPIKAR SYNDET AP+

Application: Entire body and face, once a day

Patient Services

FOR KIDS AND PARENTS

Explore the eczema academy, a challenge designed to help kids stay consistent, thereby ensuring the treatment delivers optimal results and reduces relapses.

Access Kids and Parents Education Materials

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