An enlarged photoprotection covering the whole UV spectrum during 1 month: clinical changes in pigmentation and wrinkles visibility through a real life split-face study

DG Mercurio, F. Flament, C. Tricaud, F. Bernerd, AL Demessant, C. Le Floc'h, N. Jager-Lezer, B. Muller, C. Delaunay.

INTRODUCTION

The current sunscreens can efficiently filter UV-wavelengths up to 370/380 nm but have limited absorption in the 370/380-400 nm range. Recently, a new cyclic merocyanine UVA1 absorber, Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate (MCE), exhibiting a maximal peak of absorption at 385 nm has been developed and was further approved by the scientific Committee on Consumer Safety(SCSS) for use. Formulations containing MCE have demonstrated a higher UVA1 protection in vitro and anti-pigmentation efficacy in vivo under controlled UV exposure.
The objective of this study was to evaluate in vivo anti-aging benefits of this broader UVA1 protection with the daily application of a sunscreen enriched with MCE for one month.