Frequency: once, repeated up to 2 times
Possible cutaneous adverse reactions: blistering, hypopigmentation, hyperpigmentation, scarring, and infection as well as discomfort during the freezing cycle
Protection from sunlight is an integral part of management of patients with AK
Werner RN, et al. Evidence- and consensus-based (S3) guidelines for the treatment of actinic keratosis – International League of Dermatological Societies in cooperation with the European Dermatology Forum – Short version. J Eur Acad Dermatol Venereol 2015;29:2069–2079.
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Werner RN, et al. Methods and Results Report – Evidence and consensus-based (S3) guidelines for the treatment of actinic keratosis – International League of Dermatological Societies in cooperation with the European Dermatology Forum. J Eur Acad Dermatol Venereol 2015;29:e1–e66.
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Due to national or regional specificities (regulatory approval, availability and treatment reimbursement policy), the international guidelines have recently been adapted.
Canada, 2015
Poulin Y, et al. for the Canadian non-melanoma skin cancer guidelines committee. Non-melanoma skin cancer in Canada. Management of actinic keratoses. J Cutan Med Surg. 2015;19(3): 227–38.
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UK, 2017
de Berker D, et al. British Association of Dermatologists’ guidelines for the care of patients with actinic keratosis 2017. Br J Dermatol 2017;176:20–43.
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France, 2019
Savary J, et al. Management and clinical practice of multiple face and scalp actinic keratosis in France. J Mark Access Health Policy 2019;7(1):1605787.
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References
Define a new AK management strategy