ACNEIFORM RASH


TYPE OF TREATMENT PROACTIVE
(PREVENTION/STEP 0) 		REACTIVE
(MANAGEMENT IN CASE OF AE)
  • Targeted therapy (EGFR inhibitors including tyrosine kinase inhibitors, MEK inhibitors, mTOR inhibitors)
  • Multikinase inhibitors
  • Gentle cleanser with PH ~ 5
  • Moisturizer
  • Sunscreen with UV broad spectrum (UVA/UVB) on all sun exposed areas. Patients with darker phototypes are at higher risk for PIH
  • Oral doxycycline (100mg BID) or minocycline when using EGFR and MEK inhibitors)
  • Continue Step 0
  • Moisturizing cream and balms
  • Barrier repair cream on face such as soothing balm, able to rebalance microbiome with ingredients such as panthenol
  • Acne dermocosmetics with niacinamide
  • Minocycline/ doxycycline
  • Topical corticosteroids after checking there is no local superinfection
  • Systemic steroids
  • If not enough, oncologist may suspend or alter treatment