PHOTOSENSITIVITY


TYPE OF TREATMENT PROACTIVE
(PREVENTION/STEP 0) 		REACTIVE
(MANAGEMENT IN CASE OF AE)
  • BRAF inhibitors
  • EGFR inhibitors
  • Multikinase inhibitors
  • Vandetanib
  • Chemotherapy (fluorouracil, dacarbazine, methotrexate, paclitaxel, vinblastine)
  • Radiation therapy
  • Gentle cleanser with pH ~ 5
  • Sun avoidance: especially direct sun at mid-day
  • Sun protection when outside with UV broad spectrum UVB/UVA SPF 50 or greater sun-screens and strong UVA protection, especially with targeted therapy; clothing, sunglasses, and hats; patients with darker phototypes are at higher risk for PIH
  • Reapply sunscreen q2h
  • Educate patient that sun can penetrate glass windows and in cloudy weather (home, car, workplace)
  • Continue Step 0
  • Cool colloidal oatmeal baths may help
  • Soothing emollients
  • Aloe vera
  • NSAIDs, other painkillers
  • Topical corticosteroids