Alopecia

    La Roche-Posay
  • May 2022
  • 5min

Therapeutic classes inducing this adverse event
Chemotherapy, SMO inhibitor, BRAF inhibitor, Antiangiogenic agent, MEK inhibitor, EGFR inhibitor, Hormone therapy, Cyclin-dependent kinase 4/6 inhibitor

Alopecia
Reduction in hair density
Reduction in hair density

CTCAE V5.0

Hair loss of up to 50% of normal for that individual that is not obvious from a distance but only on close inspection; a different hair style may be required to cover the hair loss but it does not require a wig or hair piece to camouflage


SIMPLIFIED GRADING

Not obvious, easy to camouflage


REFERENCES

Peuvrel L, Cassecuel J, Bernier C, Quéreux G, Saint-Jean M, Le Moigne M, Frénard C, Khammari A, Dréno B; Supported by GESTIM Nantes group of cutaneous adverse events induced by cancer treatments. TOXICAN: a guide for grading dermatological adverse events of cancer treatments. Support Care Cancer. 2018;26:2871-7.

CTCAE V5.0

Hair loss of >50% normal for that individual that is readily apparent to others; a wig or hair piece is necessary if the patient desires to completely camouflage the hair loss; associated with psychosocial impact.


SIMPLIFIED GRADING

Readily apparent OR Psychosocial impact.


REFERENCES

Peuvrel L, Cassecuel J, Bernier C, Quéreux G, Saint-Jean M, Le Moigne M, Frénard C, Khammari A, Dréno B; Supported by GESTIM Nantes group of cutaneous adverse events induced by cancer treatments. TOXICAN: a guide for grading dermatological adverse events of cancer treatments. Support Care Cancer. 2018;26:2871-7.

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