Folliculitis

    La Roche-Posay
  • May 2022
  • 20min

Therapeutic classes inducing this adverse event
EGFR inhibitor, MEK inhibitor, mTOR inhibitor

CTCAE V5.0

Papules and/or pustules covering <10% BSA, which may or may not be associated with symptoms of pruritus or tenderness


SIMPLIFIED GRADING

<10% BSA

No or few symptoms


References

Peuvrel L, Cassecuel J, Bernier C, Quéreux G, Saint-Jean M, Le Moigne M, Frénard C, Khammari A, Dréno B; Supported by GESTIM Nantes group of cutaneous adverse events induced by cancer treatments. TOXICAN: a guide for grading dermatological adverse events of cancer treatments. Support Care Cancer. 2018;26:2871-7.

CTCAE V5.0

Papules and/or pustules covering 10 - 30% BSA, which may or may not be associated with symptoms of pruritus or tenderness; associated with psychosocial impact; limiting instrumental ADL; papules and/or pustules covering >30% BSA with or without mild symptoms


SIMPLIFIED GRADING

10-30% BSA or >30% BSA with no or mild symptoms OR Limiting instrumental ADL OR Psychosocial impact


References

Peuvrel L, Cassecuel J, Bernier C, Quéreux G, Saint-Jean M, Le Moigne M, Frénard C, Khammari A, Dréno B; Supported by GESTIM Nantes group of cutaneous adverse events induced by cancer treatments. TOXICAN: a guide for grading dermatological adverse events of cancer treatments. Support Care Cancer. 2018;26:2871-7.

CTCAE V5.0

Papules and/or pustules covering >30% BSA, with moderate or severe symptoms; limiting self care ADL; associated with local superinfection with oral antibiotics indicated


SIMPLIFIED GRADING

>30% BSA with moderate or severe symptoms OR Limiting self care ADL


References

Peuvrel L, Cassecuel J, Bernier C, Quéreux G, Saint-Jean M, Le Moigne M, Frénard C, Khammari A, Dréno B; Supported by GESTIM Nantes group of cutaneous adverse events induced by cancer treatments. TOXICAN: a guide for grading dermatological adverse events of cancer treatments. Support Care Cancer. 2018;26:2871-7.

CTCAE V5.0

Life-threatening consequences; papules and/or pustules covering any % BSA, which may or may not be associated with symptoms of pruritus or tenderness and are associated with extensive superinfection with IV antibiotics indicated


SIMPLIFIED GRADING

Life-threatening consequences, mainly in connection with superinfection


References

Peuvrel L, Cassecuel J, Bernier C, Quéreux G, Saint-Jean M, Le Moigne M, Frénard C, Khammari A, Dréno B; Supported by GESTIM Nantes group of cutaneous adverse events induced by cancer treatments. TOXICAN: a guide for grading dermatological adverse events of cancer treatments. Support Care Cancer. 2018;26:2871-7.

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