Hypertrichosis

    La Roche-Posay
  • May 2022
  • 10min

Therapeutic classes inducing this adverse event
EGFR inhibitor, MEK inhibitor, Hormone therapy

Hypertrichosis
Abnormal increase in hair density or length
Abnormal increase in hair density or length

CTCAE V5.0

Increase in length, thickness or density of hair that the patient is either able to camouflage by periodic shaving or removal of hairs or is not concerned enough about the overgrowth to use any form of hair removal

SIMPLIFIED GRADING

Not obvious, easy to camouflage


References

Peuvrel L, Cassecuel J, Bernier C, Quéreux G, Saint-Jean M, Le Moigne M, Frénard C, Khammari A, Dréno B; Supported by GESTIM Nantes group of cutaneous adverse events induced by cancer treatments. TOXICAN: a guide for grading dermatological adverse events of cancer treatments. Support Care Cancer. 2018;26:2871-7.

CTCAE V5.0

Increase in length, thickness or density of hair at least on the usual exposed areas of the body [face (not limited to beard/moustache area) plus/minus arms] that requires frequent shaving or use of destructive means of hair removal to camouflage; associated with psychosocial impact

SIMPLIFIED GRADING

Visible, requires hair removal (shaving, epilation, etc.) to camouflage OR Mechanical eye irritation secondary to trichomegaly OR Psychosocial impact


References

Peuvrel L, Cassecuel J, Bernier C, Quéreux G, Saint-Jean M, Le Moigne M, Frénard C, Khammari A, Dréno B; Supported by GESTIM Nantes group of cutaneous adverse events induced by cancer treatments. TOXICAN: a guide for grading dermatological adverse events of cancer treatments. Support Care Cancer. 2018;26:2871-7.

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