Skin hypopigmentation

    La Roche-Posay
  • May 2022
  • 10min

Therapeutic classes inducing this adverse event
CTLA4 inhibitor, PD-1 inhibitor, Antiangiogenic agent, KIT inhibitor

Skin hypopigmentation
Depigmented macules, vitiligo
Depigmented macules, vitiligo

CTCAE V5.0

Hypopigmentation or depigmentation covering <10% BSA no psychosocial impact

SIMPLIFIED GRADING

<10% BSA

Not obvious



References

Peuvrel L, Cassecuel J, Bernier C, Quéreux G, Saint-Jean M, Le Moigne M, Frénard C, Khammari A, Dréno B; Supported by GESTIM Nantes group of cutaneous adverse events induced by cancer treatments. TOXICAN: a guide for grading dermatological adverse events of cancer treatments. Support Care Cancer. 2018;26:2871-7.

CTCAE V5.0

Hypopigmentation or depigmentation covering >10% BSA; associated psychosocial impact

SIMPLIFIED GRADING

>10% BSA OR Psychosocial impact



References

Peuvrel L, Cassecuel J, Bernier C, Quéreux G, Saint-Jean M, Le Moigne M, Frénard C, Khammari A, Dréno B; Supported by GESTIM Nantes group of cutaneous adverse events induced by cancer treatments. TOXICAN: a guide for grading dermatological adverse events of cancer treatments. Support Care Cancer. 2018;26:2871-7.

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