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Zinc oxide: Basic clinical study information
- 60min
- May. 2022
- Supported by
Abstract
Objective: To evaluate the efficacy and safety of microfine zinc oxide as a broad-spectrum photoprotective agent for use in sunscreens.
Methodology: Attenuation spectrum was assessed by means of standard spectrophotometric methods. SPF contribution was evaluated according to Food and Drug Administration standards. Photostability was measured in-vitro by assessing SPF before and after various doses of Ultra Violet Radiation (UVR). Photoreactivity was evaluated by subjecting a microfine zinc oxide/organic sunscreen formulation to escalating doses of UVR and determining the percentage of organic sunscreen remaining.
Results: Microfine zinc oxide shows absorption throughout the UVR spectrum, including UVA. It is photostable and does not react with organic sunscreens under irradiation.
Key Points: Zinc oxide is a safe, stable, nonreactive, broad-spectrum sunscreen ingredient that stays on top of skin. It is easy to formulate together with other sunscreens and can readily be used in daily care or beach products including waterproof formulations.
Pinnell, Sheldon; Mitchnick, Mark; Fairhurst, David