New Anti-Pollution Benefits of a Serum with Ascorbic Acid, Ferulic Acid, and Tocopherol in a Human Clinical Trial

G. Valacchi, S. Lynch, S. Anderias, S. White, P. Brieva, X. Yan

INTRODUCTION

Exposure to environmental stressors like particulate matter (PM) and ultraviolet radiation (UV) induces oxidative stress and inflammation in skin and leads to skin barrier dysfunction and premature aging. Metals like iron and/or copper are abundant in PM and are known to contribute to the formation of reactive oxygen species (ROS), which eventually lead to skin damage. Although the use of topical antioxidants has been suggested to help in preventing skin damage, very limited clinical studies have been performed.