INTRODUCTION

Acne vulgaris is an inflammatory disease with a complex etiology. In addition to increased sebum production, an important contributor to the pathogenesis of acne is proposed to be hyperkeratinization of the follicles. This leads to clogged, enlarged pores and a favorable environment for C. acnes bacteria and ultimately propagates the inflammatory component of the condition.^1,2 Post-inflammatory hyperpigmentation (PIH) or erythema (PIE) is often a consequence of acne in areas where excessive cutaneous inflammation has occurred.³ Treatments containing ingredients such as retinoids or glycolic acid are effective in addressing PIH, however often are harsh on sensitive skin; and in some case may even contribute to PIH.⁴ There is a need for milder, yet effective treatments to address these concerns. The goal of the present study was to evaluate the efficacy and tolerability of a moisturizer containing 3% azelaic acid, 2% α-arbutin, niacinamide and botanical extracts on oily, blemish-prone skin with PIH or erythema.