A dermocosmetic significantly improves acne flares and quality of life during menstrual cycles

E. Bagatin, A. Veriato, M. Mesrobian, E. Gilbert, C. Deloche, S. Leclerc-Mercier, C. Zouboulis

INTRODUCTION & OBJECTIVES

Few clinical studies have shown that adult female acne may worsen during the luteal (premenstrual) period of the menstrual cycle (MC). Elevated progesterone levels may be transformed into elevated testosterone levels.^1,2 The latter stimulates the androgen receptors present on sebocytes, resulting in an increased sebum quantity and a change in its composition leading to flares of non inflammatory lesions and inflammatory lesions.^3,4