COLLAGEN SCIENCE

Collagen is the most abundant protein in the body, accounting for as much as 30% of the total body mass. Collagen is diverse: in the skin, there is not 1 but 16 collagens, all bonded together to create a matrix. They can be classified into 4 families, according to their location in the skin and their role: junctional collagens, bonding collagens, initiator collagens and pillar collagens.

SAFE FORMULA TO HYDRATE THE SKIN & TARGET AGEING SIGNS

Publications

• International consensus on anti-aging dermocosmetics and skincare for clinical practice
  Zoe D Draelos, Liu Wei, Mukta Sachdev, Bruna S F Bravo, Vasanop Vachiramon, Marie Jourdan, Martina Kerscher, Catherine Delva, & Stephanie Leclerc-Mercier. International Consensus on Anti-Aging Dermocosmetics and Skin Care for Clinical Practice Using the RAND/UCLA Appropriateness Method. Journal of Drugs in Dermatology. 2024;23(1):1337-1343.
  https://doi.org/10.36849/jdd.7798
• An In vitro Comparison with Retinol, Retinoic Acid and Vitamin C. 

Juchaux, F., Deloche-Bensmaine, C., Chagnoleau, C., Kovylkina, N., El Haddad, G., Guerin, L., & Caberlotto, E. (2026). Unveiling the Anti-aging Potential of a mix of Grifola frondosa, Peptides, and Rhamnose: Epidermal and Dermal Rejuvenation Performance. An In vitro Comparison with Retinol, Retinoic Acid and Vitamin C. Annals of Dermatological Research, 004–013.https://doi.org/10.29328/journal.adr.1001039

• Impact of targeting collagen diversity on skin aging signs

Juchaux F, Martinuzzi T, Guerin L, et al. Impact of targeting collagen diversity on skin aging signs: a pilot study. J Dermat Cosmetol. 2025;9(2):37-40. DOI: 10.15406/jdc.2025.09.00288

• A co-bonding technology combining Maitake, a peptide complex, and rhamnose stimulates different skin collagens

Juchaux F, Martinuzzi T, Deloche-Bensmaine C, et al. A co-bonding technology combining Maitake, a peptide complex, and rhamnose stimulates different skin collagens and partially restores age-associated alterations: results from in vitro assays and a 3D reconstructed skin model. J Dermat Cosmetol. 2026;10(1):1‒9. DOI: 10.15406/jdc.2026.10.00310