Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris.

Abstract

This study evaluated the tolerance and efficacy of 2 facial skin products in subjects with acne using the following acne treatments:

1. treatment A, a combination of salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and idiotic acid, and
2. treatment B (BenzaClin, clindamycin 1% and benzoyl peroxide 5% gel). The treatment design included the split-face application of treatment A and treatment B and the full-face application of the cleanser, moisturizer, and sunscreen. Data were collected through physician visual assessments, subject irritation questionnaires ans assessments, along with clinical photography. Results showed similar tolerance and efficacy for both treatments.

Journal of Drugs and Dermatology, 2013;12(3):266-269

Leslie S. Baumann, MD, CPI; Kristian Fugucras, MS; Amanda Dahl, BS, CCRA; Margarita Yatskayer, MS; Christian Oresajo, PhD