Bibliographie : Atopie

Études cliniques avec émollients

  • Gelmetti C., Grimalt R., Bieber T. et al. Emollient as adjunctive therapy in the management of atopic dermatitis: a multicentric clinical study.
    Conducted in 131 children with mild to moderate AD, this international and multicentric trial shows the importance of emollient as adjunctive therapy in atopic dermatitis.
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  • Rougier A., Seite S. European observational study on the management of atopic dermatitis children.
    To evaluate the management of atopic children in private practice, dermatologists from 7 European countries were asked about their management of 1,718 children with mild to moderate AD.
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  • Gelmetti C., Boralevi F. Seite S. et al. Quality of life of parents living with a child suffering from atopic dermatitis before and after a 3-month treatment with an emollient.
    To evaluate the impact of a three-month treatment with an emollient on their QoL, 191 parents living with an atopic dermatitis child were asked by their dermatologist.
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  • Bissonnette R., Marchessault P., Rougier A., Seite S. Evaluation of tolerance and efficacy of a new moisturizer in children with atopic dermatitis.
    35 children with active AD participated in this clinical trial designed to assess the tolerance and efficacy of an emollient containing an anti-inflammatory ingredient (niacinamide).
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  • Seite S., Zelenkova H., Martin R., Fierer N. Using a specific emollient to manage skin microbiome dysbiosis.
    This study used a high-throughput sequencing approach targeting a portion of the 16S rRNA gene to measure how an emollient containing a biomass of a specific non-pathogenic bacteria may regulate skin microbiome….
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  • Flores G.E., Seite S., Henley J.B. et al. Response of skin microbiome to emollient treatment in patients with atopic dermatitis.
    This study was designed to characterize intra-individually specific microbiota associated with the clinical symptoms of atopic dermatitis before and after a three-month treatment with an emollient.
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Thérapies adjuvantes

  • Ellis C., Luger T. On behalf of the ICCAD II Faculty. International Consensus Conference on Atopic Dermatitis (ICCAD II): clinical update and current treatment strategies. Br J Dermatol. 2003;148(Suppl.63):3–10.
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  • Schäfer L., Kragballe K. Abnormalities in epidermal lipid metabolism in patients with atopic dermatitis. J Invest Dermatol. 1991 Jan;96(1):10–5.
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  • Imokawa G., Abe A. Jin K. et al. Decreased level of ceramides in stratum corneum of atopic dermatitis: an etiologic factor in atopic dry skin? J Invest Dermatol. 1991 Apr;96(4):523–6.
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  • McGrath J.A., Uitto J. The filaggrin story: novel insights into skin-barrier function and disease. Trends Mol Med. 2008 Jan;14(1):20–7.
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  • Olsson M, Broberg A., Jermas M. et al. Increased expression of aquaporin 3 in atopic eczema. Allergy. 2006 Sep;61(9):1132–7.
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  • Sator P.G., Schmidt J.B., Hönigsmann H. Comparison of epidermal hydration and skin surface lipids in healthy individuals and in patients with atopic dermatitis. J Am Acad Dermatol. 2003 Mar;48(3):352–8.
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  • Grimalt R., Mengeaud V., Cambazard F. et al. The steroid-sparing effect of an emollient therapy in infants with atopic dermatitis: a randomized controlled study. Dermatology. 2007;214(1):61–7.
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  • Msika P., De Belilovsky C., Piccardi N. et al. New emollient with topical corticosteroid-sparing effect in treatment of childhood atopic dermatitis: SCORAD and quality of life improvement. Pediatr Dermatol 2008 Nov–Dec;25(6):606–12.
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  • Darsow U., Wollenberg A., Simon D. et al. ETFAD/EADV eczema task force 2009 position paper on diagnosis and treatment of atopic dermatitis. J Eur Acad Dermatol Venereol. 2010 Mar;24(3):317–28.
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  • Corazza M., Lauriola M.M., Zappaterra M. et al. Surfactants, skin cleansing protagonists. J Eur Acad Dermatol Venereol 2010 Jan;24(1): 1–6.
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  • Shaughnessy C.N., Malajian D., Belsito D.V. Cutaneous delayed-type hypersensitivity in patients with atopic dermatitis: reactivity to surfactants. J Am Acad Dermatol 2014 Apr;70(4):704–8.
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  • Meckfessel M.H., Brandt S. The structure, function, and importance of ceramides in skin and their use as therapeutic agents in skin-care products. J Am Acad Dermatol 2014 Jul;71(1):177–84.
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  • Chen Y.E., Tsao H. The skin microbiome: current perspectives and future challenges. J Am Acad Dermatol 2013 Jul;69(1):143–55.
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  • Bouwstra J.A., Ponec M. The skin barrier in healthy and diseased state. Biochim Biophys Acta 2006 Dec;1758(12):2080–95.
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  • Elias P.M., Schmuth M. Abnormal skin barrier in the etiopathogenesis of atopic dermatitis. Curr Opin Allergy Clin Immunol 2009 Oct;9(5):437–46.
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  • Guo Q 1, Liang F , Tian L , Schikowski T , Liu W , Pan X . Ambient air pollution and the hospital outpatient visits for eczema and dermatitis in Beijing: a time-stratified case-crossover analysis. Environ Sci Process Impacts. 2019 Jan 23;21(1):163-173.
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Recommnadations sur la prise en charge de la dermatite atopique

  • Ellis C., Luger T. On behalf of the ICCAD II Faculty. International Consensus Conference on Atopic Dermatitis II (ICCAD II*): clinical update and current treatment strategies. Br J Dermatol. 2003;148 (Suppl. 63):3–10.
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  • Akdis C.A., Akdis M.B., Bieber T. et al. Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report. J Allergy Clin Immunol 2006;118:152–69.
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  • Rubel D., Thirumoorthy T. Soebaryo R.W. et al. Asia–Pacific Consensus Group for Atopic Dermatitis. Consensus guidelines for the management of atopic dermatitis: An Asia–Pacific perspective. Journal of Dermatology 2013;40:1–12.
  • Sidbury R., Tom W.L., Bergman J.N. et al. Guidelines of care for the management of atopic dermatitis: Section 4. Prevention of disease flares and use of adjunctive therapies and approaches. J Am Acad Dermatol. 2014 Dec;71(6):1218–33.
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  • Wollenberg A., Oranje A., Deleuran M. et al. ETFAD/EADV Eczema task force 2015 position paper on diagnosis and treatment of atopic dermatitis in adult and paediatric patients. JEADV 2016;30:729–47.
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Microbiome cutané et émollients dans la dermatite atopique

  • Baldwin H.E., Bhatia N.D., Friedman A. et al. The Role of Cutaneous Microbiota Harmony in Maintaining a Functional Skin Barrier. J Drugs Dermatol. 2017;16(1):12–8.
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  • Flores G.E., Seite S., Henley J.B. et al. Microbiome of Affected and Unaffected Skin of Patients With Atopic Dermatitis Before and After Emollient Treatment. J Drugs Dermatol. 2014;13(11):611–8.
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  • Seite S., Bieber T. Barrier function and microbiotic dysbiosis in atopic dermatitis. Clinical, Cosmetic and Investigational Dermatology 2015;8:479–83.
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  • Lynde C.W., Andriessen A., Bertucci V. et al. The skin microbiome in atopic dermatitis and its relationship with emollients. J Cutan Med Surg. 2016;20(1):21–8.
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  • Grice E.A., Kong H.H., Conlan S. et al. Topographical and temporal diversity of the human skin microbiome. Science 2009;324(5931):1190–2.
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  • Human Microbiome Jumpstart Reference Strains Consortium, Nelson K.E., Weinstock G.M., Highlander S.K. et al. A catalog of reference genomes from the human microbiome. Science 2010;328(5981):994–9.
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  • Grice E.A., Segre J.A. The human microbiome: our second genome. Annu Rev Genomics Hum Genet. 2012;13:151–70.
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  • Grice E.A., Segre J.A. The skin microbiome. Nat Rev Microbiol. 2011;9(8):244–53.
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  • Zhou Y., Gao H., Mihindukulasuriya K.A. et al. Biogeography of the ecosystems of the healthy human body. Genome Biol. 2013;14(1):R1.
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  • Di Domenico EG, Cavalo I, Capitanio B, et al. Staphylococcus aureus and the cutaneous microbiota biofilms in the pathogenesis of atopic dermatitis. Microorganisms 2019;7(9).
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