HOW TO SUPPORT SKIN DURING MEDICAL WEIGHT LOSS

    Laboratoires Vichy
  • Jul 2026
  • 2min

GLP-1 (Glucagon-Like Peptide-1) and GIP (Glucose-Dependent Insulinotropic Polypeptide) are natural incretin hormones that play a crucial role in our metabolic system. Modern therapies mimic these hormones to regulate appetite, delay gastric emptying, and enhance insulin secretion, resulting in highly effective and rapid weight loss.

However, this rapid weight loss has a direct and challenging counterpart on the skin. Because the transition is so sudden, the skin's elasticity cannot keep pace with the reduction of facial adipose tissue. This rapid deflation leads to a visible collapse of the dermal matrix, observed by doctors as:

• "Ozempic Face": Sudden hollowing of the cheeks and under-eye area.
• Loss of Firmness: Pronounced sagging along the jawline and neck.
• Deepened Wrinkles: Accelerated lines and dryness due to a compromised barrier and decreased collagen.

Liftactiv Collagen Specialist 16's efficacy in preventing facial volume loss is revealed in a new in vivo and in vitro study. The research showed unprecedented support for the skin's structure and collagen families during medical weight loss.

Learn more about counteracting GLP-1 skin side effects with our experts Elisa Caberlotto, Vichy Global Scientific Director, and Ilaria Collini, Vichy Global Communication Manager.

Liftactiv Collagen Specialist 16 targets the skin's architecture directly thanks to its 3 complementary ingredients:

• Matrixyl™: supports extracellular matrix
• Maitake: prevents oxidative stress
• Rhamnose: increases dermal thickness

Discover more about Liftactiv Collagen Specialist 16 here: