
M89PF contains Vichy volcanic mineralizing water and probiotic fractions and is beneficial in facial skin stressed by ablative procedures and facial skin manifestations: results from an observational study performed in Southeast Asia
Stéphanie Leclerc-Mercier, Frédéric Flament, Delphine Kerob, Marita Kosmadaki, Elia Roó, Thierry Haag, Christos C. Zouboulis

RATIONALE AND OBJECTIVES
The decline in estrogen levels from several years before (perimenopause) and during menopause has various negative effects, including skin specific issues, which can affect quality of life (QoL).1
The objective of this open study was to evaluate two specifically designed anti-aging dermocosmetic regimens (day cream, night cream and serum), containing key ingredients (proxylane and cassia extract), for women during the perimenopause or menopause.