



Delphine Kerob, Priscila Correia, Stéphanie Leclerc-Mercier, José Junior, Erika Fernandes, Luana Lopes, Camila Valpaços, Diego Svoboda, Jerry Tan MD
INTRODUCTION
Tretinoin is a topical gold standard for skin aging, particularly photoaging. However, as for any topical retinoid, patient satisfaction and adherence can be impaired by local tolerability issues in the first 1-2 weeks.1,2
The M89PF containing volcanic mineralizing water, probiotic fractions, hyaluronic acid, niacinamide and tocopherol has been developed to reinforce the skin barrier and enhance skin defenses against exposome stressors, such as application of topical retinoids.3